Natural compounds from freshwater mussels disrupt fungal virulence determinants and influence fluconazole susceptibility in the presence of macrophages in Cryptococcus neoformans
ABSTRACTCryptococcus neoformans is a human fungal pathogen responsible for fatal infections, especially in patients with a depressed immune system. Overexposure to antifungal drugs due to prolonged treatment regimens and structure-similar applications in agriculture have weakened the efficacy of cur...
Main Authors: | Davier Gutierrez-Gongora, Michael Woods, Ryan S. Prosser, Jennifer Geddes-McAlister |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2024-03-01
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Series: | Microbiology Spectrum |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/spectrum.02841-23 |
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