Discovery of a gene cluster for the biosynthesis of novel cyclic peptide compound, KK-1, in Curvularia clavata

Discovery of a gene cluster for the biosynthesis of novel cyclic peptide compound, KK-1, in Curvularia clavata

KK-1, a cyclic depsipeptide with 10 residues produced by a filamentous fungus Curvularia clavata BAUA-2787, is a promising pesticide active compound with high activity against many plant pathogens, especially Botrytis cinerea. As a first step toward the future mass production of KK-1 through synthet...

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Bibliographic Details
Main Authors: Shigenari Yamaguchi, Tomonori Fujioka, Akira Yoshimi, Toshitaka Kumagai, Maiko Umemura, Keietsu Abe, Masayuki Machida, Kiyoshi Kawai
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Fungal Biology
Subjects:
non-ribosomal peptide
biosynthetic gene cluster
antifungal agent
genome sequence
Curvularia clavata
natural fungicide
Online Access:https://www.frontiersin.org/articles/10.3389/ffunb.2022.1081179/full

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https://www.frontiersin.org/articles/10.3389/ffunb.2022.1081179/full

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