Polycomb repressive complex 2 and its core component EZH2: potential targeted therapeutic strategies for head and neck squamous cell carcinoma

Polycomb repressive complex 2 and its core component EZH2: potential targeted therapeutic strategies for head and neck squamous cell carcinoma

Abstract The polycomb group (PcG) comprises a set of proteins that exert epigenetic regulatory effects and play crucial roles in diverse biological processes, ranging from pluripotency and development to carcinogenesis. Among these proteins, enhancer of zeste homolog 2 (EZH2) stands out as a catalyt...

Full description

Bibliographic Details
Main Authors: Yuxi Cheng, Zhengzheng Song, Xiaodan Fang, Zhangui Tang
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Clinical Epigenetics
Subjects:
Head and neck squamous cell carcinoma
PRC2
EZH2
Polycomb repressive complex
Transcription regulation
EMT
Online Access:https://doi.org/10.1186/s13148-024-01666-2

Internet

https://doi.org/10.1186/s13148-024-01666-2

Similar Items