β-Caryophyllene Mitigates Collagen Antibody Induced Arthritis (CAIA) in Mice Through a Cross-Talk between CB2 and PPAR-γ Receptors

β-Caryophyllene Mitigates Collagen Antibody Induced Arthritis (CAIA) in Mice Through a Cross-Talk between CB2 and PPAR-γ Receptors

β-caryophyllene (BCP) is a cannabinoid receptor 2 (CB2) agonist that tempers inflammation. An interaction between the CB2 receptor and peroxisome proliferator-activated receptor gamma (PPAR-γ) has been suggested and PPAR-γ activation exerts anti-arthritic effects. The aim...

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Bibliographic Details
Main Authors: Natasha Irrera, Angela D’Ascola, Giovanni Pallio, Alessandra Bitto, Emanuela Mazzon, Federica Mannino, Violetta Squadrito, Vincenzo Arcoraci, Letteria Minutoli, Giuseppe Maurizio Campo, Angela Avenoso, Elisa Benedetta Bongiorno, Mario Vaccaro, Francesco Squadrito, Domenica Altavilla
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Biomolecules
Subjects:
β-caryophyllene
CB2 receptors
PPAR-γ
CAIA
arthritis
Online Access:https://www.mdpi.com/2218-273X/9/8/326

Internet

https://www.mdpi.com/2218-273X/9/8/326

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