Multiple-Gene Regulation for Enhanced Antitumor Efficacy with Branch-PCR-Assembled TP53 and MYC Gene Nanovector

Multiple-Gene Regulation for Enhanced Antitumor Efficacy with Branch-PCR-Assembled TP53 and MYC Gene Nanovector

Multiple proteins are involved in network regulation through the crosstalk of different signaling pathways in cancers. Here, we propose a novel strategy of genome therapy with branch-PCR-assembled gene nanovectors to perform network-based gene regulation at multiple levels for cancer therapy. To val...

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Bibliographic Details
Main Authors: Longhuai Cheng, Liqing Lu, Ziyi Chen, Dejun Ma, Zhen Xi
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Molecules
Subjects:
branch-PCR
gene therapy
TP53
MYC
genome therapy
cancer therapy
Online Access:https://www.mdpi.com/1420-3049/27/20/6943

Internet

https://www.mdpi.com/1420-3049/27/20/6943

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