Progranulin promoted the proliferation, metastasis, and suppressed apoptosis via JAK2-STAT3/4 signaling pathway in papillary thyroid carcinoma
Abstract Background Progranulin (PGRN), a glycoprotein secreted by a wide range of epithelial cells and plays an important role in inflammatory mechanisms and tumor progression. In this study, the expression, and functions of PGRN in papillary thyroid carcinoma (PTC) was examined to explore the pote...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-09-01
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Series: | Cancer Cell International |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12935-023-03033-2 |