Toxoplasma gondii induces MST2 phosphorylation mediating the activation of hippo signaling pathway to promote apoptosis and lung tissue damage

Toxoplasma gondii induces MST2 phosphorylation mediating the activation of hippo signaling pathway to promote apoptosis and lung tissue damage

Summary: Toxoplasma gondii (T. gondii) is an intracellular parasite, and its regulation of host cell apoptosis directly affects its parasitism. Studies link T. gondii-induced apoptosis to abnormal expression of mammalian STE20-like protein kinase 2 (MST2), but its precise role remains unclear. In th...

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Bibliographic Details
Main Authors: Kangzhi Xu, Shifan Zhu, Fan Xu, Jin Yang, Bin Deng, Dingzeyang Su, Jing Ma, Mingyue Zu, Yifan Lin, Tianxu Pei, Yuyang Zhu, Lele Wang, Dandan Liu, Qiangde Duan, Jinjun Xu, Zhiming Pan, Jianping Tao, Zhaofeng Hou
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:iScience
Subjects:
Molecular biology
Microbiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224025379

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http://www.sciencedirect.com/science/article/pii/S2589004224025379

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