Inclusiveness of the All of Us Research Program improves polygenic risk scores and fosters genomic medicine for all

Polygenic risk scores (PRS) show promise but have accuracy disparities across ancestries due to underrepresentation in the existing genomic databases. Here, we outline the initiative of All of Us Research Program in refining PRS and advancing genomic medicine for all.

Bibliographic Details
Main Authors: Benson R. Kidenya, Gerald Mboowa
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-024-00647-z