Treatment with afobazole at delayed time points following ischemic stroke improves long-term functional and histological outcomes

Treatment with afobazole at delayed time points following ischemic stroke improves long-term functional and histological outcomes

There is currently a significant lack of therapeutic options for acute ischemic stroke, and no drug has been approved for treating patients at delayed time points (≥6 h post-stroke). Afobazole, an anxiolytic currently used clinically in Russia, has been shown to reduce neuronal and glial cell injury...

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Bibliographic Details
Main Authors: C. Katnik, A. Garcia, A.A. Behensky, I.E. Yasny, A.M. Shuster, S.B. Seredenin, A.V. Petrov, S. Seifu, J. McAleer, A. Willing, J. Cuevas
Format: Article
Language:English
Published: Elsevier 2014-02-01
Series:Neurobiology of Disease
Subjects:
Ischemic stroke
Afobazole
Middle cerebral artery occlusion
Sigma receptor
Behavior
Neuroprotection
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996113002866

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http://www.sciencedirect.com/science/article/pii/S0969996113002866

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