Theoretical Design and Synthesis of Caged Compounds Using X‐Ray‐Triggered Azo Bond Cleavage

Theoretical Design and Synthesis of Caged Compounds Using X‐Ray‐Triggered Azo Bond Cleavage

Abstract Caged compounds are frequently used in life science research. However, the light used to activate them is commonly absorbed and scattered by biological materials, limiting their use to basic research in cells or small animals. In contrast, hard X‐rays exhibit high bio‐permeability due to th...

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Bibliographic Details
Main Authors: Koki Ogawara, Osamu Inanami, Hideo Takakura, Kenichiro Saita, Kohei Nakajima, Sonu Kumar, Naoya Ieda, Masato Kobayashi, Tetsuya Taketsugu, Mikako Ogawa
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Advanced Science
Subjects:
azo compounds
cancer
cleavage reaction
radical reactions
reaction mechanism
Online Access:https://doi.org/10.1002/advs.202306586

Internet

https://doi.org/10.1002/advs.202306586

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