Fibronectin (FN) cooperated with TLR2/TLR4 receptor to promote innate immune responses of macrophages via binding to integrin β1

Macrophages could adhere to extracellular matrix molecules(ECM) to induce the expression of pro-inflammatory mediators and phagocytosis that contribute to the pathogenesis of pulmonary infection diseases. Fibronectin (FN) is a large glycoprotein capable of interacting with various ECM molecules prod...

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Bibliographic Details
Main Authors: Dongsheng Fei, Xianglin Meng, Wei Yu, Songlin Yang, Ning Song, Yanhui Cao, Songgen Jin, Lina Dong, Shangha Pan, Mingyan Zhao
Format: Article
Language:English
Published: Taylor & Francis Group 2018-12-01
Series:Virulence
Subjects:
Online Access:http://dx.doi.org/10.1080/21505594.2018.1528841