Fibronectin (FN) cooperated with TLR2/TLR4 receptor to promote innate immune responses of macrophages via binding to integrin β1
Macrophages could adhere to extracellular matrix molecules(ECM) to induce the expression of pro-inflammatory mediators and phagocytosis that contribute to the pathogenesis of pulmonary infection diseases. Fibronectin (FN) is a large glycoprotein capable of interacting with various ECM molecules prod...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2018-12-01
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Series: | Virulence |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/21505594.2018.1528841 |