Multiomics analysis of tumor mutational burden across cancer types

Multiomics analysis of tumor mutational burden across cancer types

Whether tumor mutational burden (TMB) is related to improved survival outcomes or the promotion of immunotherapy in various malignant tumors remains controversial, and we lack a comprehensive understanding of TMB across cancers. Based on the data obtained from The Cancer Genome Atlas (TCGA), we cond...

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Bibliographic Details
Main Authors: Lin Li, Long Bai, Huan Lin, Lin Dong, Rumeng Zhang, Xiao Cheng, Zexian Liu, Yi Ouyang, Keshuo Ding
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Tumor mutational burden (TMB)
Molecular alterations
Differential expression
Signaling pathway
Immunology
Survival
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037021004359

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http://www.sciencedirect.com/science/article/pii/S2001037021004359

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