Pathophysiological Potentials of NRF3-Regulated Transcriptional Axes in Protein and Lipid Homeostasis

Pathophysiological Potentials of NRF3-Regulated Transcriptional Axes in Protein and Lipid Homeostasis

NRF3 (NFE2L3) belongs to the CNC-basic leucine zipper transcription factor family. An NRF3 homolog, NRF1 (NFE2L1), induces the expression of proteasome-related genes in response to proteasome inhibition. Another homolog, NRF2 (NFE2L2), induces the expression of genes related to antioxidant responses...

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Bibliographic Details
Main Authors: Tsuyoshi Waku, Akira Kobayashi
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
NRF3
protein homeostasis
lipid homeostasis
proteasome
translation
GGPP
Online Access:https://www.mdpi.com/1422-0067/22/23/12686

Internet

https://www.mdpi.com/1422-0067/22/23/12686

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