Synthesis, characterization, anticancer, anti-inflammatory activities, and docking studies of 3,5-disubstituted thiadiazine-2-thiones

Synthesis, characterization, anticancer, anti-inflammatory activities, and docking studies of 3,5-disubstituted thiadiazine-2-thiones

In the search for potent bioactive compounds, a series of tetrahydro-2H-1,3,5-thiadiazine-2-thiones (1–13) were synthesized in good yield and characterized by means of 1H NMR, 13C NMR, and mass spectral data. The anticancer activity of the compounds was evaluated against HeLa cell line and anti-infl...

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Bibliographic Details
Main Authors: Ali Haleema, Khan Rasool, Pan Xiandao, Shaheen Farzana, Jabeen Almas, Rauf Abdur, Shah Muhammad, Rashid Umer, Al-Awthan Yahya S., Bahattab Omar S., Al-Duais Mohammed A., Mubarak Mohammad S.
Format: Article
Language:English
Published: De Gruyter 2023-03-01
Series:Green Processing and Synthesis
Subjects:
thiadiazine thione
inducible nitric oxide synthase
hela cell line
docking studies
Online Access:https://doi.org/10.1515/gps-2022-8136

Internet

https://doi.org/10.1515/gps-2022-8136

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