Analysis of Monoclonal Antibodies by Capillary Electrophoresis: Sample Preparation, Separation, and Detection

Analysis of Monoclonal Antibodies by Capillary Electrophoresis: Sample Preparation, Separation, and Detection

Therapeutic monoclonal antibodies (mAbs) are dominating the biopharmaceutical field due to the fact of their high specificity in the treatment of diverse diseases. Nevertheless, mAbs are very complex glycoproteins exhibiting several macro- and microheterogeneities that may affect their safety, quali...

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Bibliographic Details
Main Authors: Meriem Dadouch, Yoann Ladner, Catherine Perrin
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Separations
Subjects:
therapeutic monoclonal antibodies
sample preparation
capillary electrophoresis
mass spectrometry
characterization
quality control
Online Access:https://www.mdpi.com/2297-8739/8/1/4

Internet

https://www.mdpi.com/2297-8739/8/1/4

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