Analysis of Monoclonal Antibodies by Capillary Electrophoresis: Sample Preparation, Separation, and Detection

Analysis of Monoclonal Antibodies by Capillary Electrophoresis: Sample Preparation, Separation, and Detection

Therapeutic monoclonal antibodies (mAbs) are dominating the biopharmaceutical field due to the fact of their high specificity in the treatment of diverse diseases. Nevertheless, mAbs are very complex glycoproteins exhibiting several macro- and microheterogeneities that may affect their safety, quali...

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Detalles Bibliográficos
Autores principales: Meriem Dadouch, Yoann Ladner, Catherine Perrin
Formato: Artículo
Lenguaje:English
Publicado: MDPI AG 2021-01-01
Colección:Separations
Materias:
therapeutic monoclonal antibodies
sample preparation
capillary electrophoresis
mass spectrometry
characterization
quality control
Acceso en línea:https://www.mdpi.com/2297-8739/8/1/4

Internet

https://www.mdpi.com/2297-8739/8/1/4

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