Sulf2a controls Shh-dependent neural fate specification in the developing spinal cord

Abstract Sulf2a belongs to the Sulf family of extracellular sulfatases which selectively remove 6-O-sulfate groups from heparan sulfates, a critical regulation level for their role in modulating the activity of signalling molecules. Data presented here define Sulf2a as a novel player in the control...

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Bibliographic Details
Main Authors: Cathy Danesin, Romain Darche-Gabinaud, Nathalie Escalas, Vanessa Bouguetoch, Philippe Cochard, Amir Al Oustah, David Ohayon, Bruno Glise, Cathy Soula
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80455-2