Identification of African Elephant Polyomavirus in wild elephants and the creation of a vector expressing its viral tumor antigens to transform elephant primary cells.

Wild elephant populations are declining rapidly due to rampant killing for ivory and body parts, range fragmentation, and human-elephant conflict. Wild and captive elephants are further impacted by viruses, including highly pathogenic elephant endotheliotropic herpesviruses. Moreover, while the rich...

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Bibliographic Details
Main Authors: Virginia R Pearson, Jens B Bosse, Orkide O Koyuncu, Julian Scherer, Cristhian Toruno, Rosann Robinson, Lisa M Abegglen, Joshua D Schiffman, Lynn W Enquist, Glenn F Rall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0244334