The role of input noise in transcriptional regulation.

Gene expression levels fluctuate even under constant external conditions. Much emphasis has usually been placed on the components of this noise that are due to randomness in transcription and translation. Here we focus on the role of noise associated with the inputs to transcriptional regulation; in...

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Bibliographic Details
Main Authors: Gasper Tkacik, Thomas Gregor, William Bialek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2475664?pdf=render