Association of GSTM1 and GSTT1 Null Genotypes with Toluene Diisocyanate-Induced Asthma

Background. Toluene diisocyanate (TDI) causes occupational asthma by generating oxidative stress, leading to tissue injury and inflammation. Glutathione transferases (GSTs) are detoxifying enzymes that eliminate oxidative stress. We examined whether the genotypes of the GSTM1 and GSTT1 genes are ass...

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Bibliographic Details
Main Authors: Jong-Uk Lee, Ji-Yeon Jeong, Min Kyung Kim, Sun A. Min, Jong-Sook Park, Choon-Sik Park
Format: Article
Language:English
Published: Hindawi Limited 2022-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2022/7977937