Pan-cancer analysis identifies migrasome-related genes as a potential immunotherapeutic target: A bulk omics research and single cell sequencing validation

Pan-cancer analysis identifies migrasome-related genes as a potential immunotherapeutic target: A bulk omics research and single cell sequencing validation

IntroductionThe migrasome is a newly discovered organelle that resembles extracellular vesicles in structure. However, the function of the migrasome in tumors, particularly in relation to tumor immunity and tumor microenvironment, is unclear.MethodsGene expression data, copy number variation raw dat...

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Bibliographic Details
Main Authors: Yan Qin, Jie Yang, Cao Liang, Jun Liu, Zhixing Deng, Binli Yan, Ying Fu, Yinghua Luo, Xiaozhen Li, Xiaoying Wei, Wei Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
migrasome
pan-cancer
tumor immunity
tumor microenvironment
immune checkpoint inhibitors
scRNA-seq
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.994828/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.994828/full

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