The role of epigenetic modifications in drug resistance and treatment of breast cancer

The role of epigenetic modifications in drug resistance and treatment of breast cancer

Abstract Background Breast cancer is defined as a biological and molecular heterogeneous disorder that originates from breast cells. Genetic predisposition is the most important factor giving rise to this malignancy. The most notable mutations in breast cancer occur in the BRCA1 and BRCA2 genes. Owi...

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Bibliographic Details
Main Authors: Mohsen Karami Fath, Ali Azargoonjahromi, Arash Kiani, Fateme Jalalifar, Parisa Osati, Mahsa Akbari Oryani, Fateh Shakeri, Farhad Nasirzadeh, Behman Khalesi, Mohsen Nabi-Afjadi, Hamidreza Zalpoor, Maysam Mard-Soltani, Zahra Payandeh
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Cellular & Molecular Biology Letters
Subjects:
Breast cancer
Epigenetic modifications
microRNAs
Treatment
Chemoresistance
Online Access:https://doi.org/10.1186/s11658-022-00344-6

Internet

https://doi.org/10.1186/s11658-022-00344-6

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