Treatment following Triple-AAV Delivery in Mature Murine Model of Human <i>CDH23</i>-Associated Hearing Loss

Treatment following Triple-AAV Delivery in Mature Murine Model of Human <i>CDH23</i>-Associated Hearing Loss

This study aimed to investigate the transduction efficiency of triple adeno-associated virus (AAV) vectors in the cochleae of adult mice, focusing on large-gene-associated hearing loss (HL). Additionally, we sought to evaluate the feasibility of cochlear gene therapy in a mouse model of human <i&...

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Bibliographic Details
Main Authors: Hidekane Yoshimura, Shu Yokota, Yutaka Takumi
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Current Issues in Molecular Biology
Subjects:
gene therapy
genetic hearing loss
adeno-associated virus
progressive hearing loss
Online Access:https://www.mdpi.com/1467-3045/45/12/590

Internet

https://www.mdpi.com/1467-3045/45/12/590

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