Analysis of neuronal injury transcriptional response identifies CTCF and YY1 as co-operating factors regulating axon regeneration

Analysis of neuronal injury transcriptional response identifies CTCF and YY1 as co-operating factors regulating axon regeneration

Injured sensory neurons activate a transcriptional program necessary for robust axon regeneration and eventual target reinnervation. Understanding the transcriptional regulators that govern this axon regenerative response may guide therapeutic strategies to promote axon regeneration in the injured n...

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Bibliographic Details
Main Authors: Oshri Avraham, Jimmy Le, Kathleen Leahy, Tiandao Li, Guoyan Zhao, Valeria Cavalli
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Molecular Neuroscience
Subjects:
axon regeneration
sensory neurons
transcription factors
bioinformatics analyses
CTCF
YY1
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.967472/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2022.967472/full

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