Application of Metagenomic Next-Generation Sequencing (mNGS) Using Bronchoalveolar Lavage Fluid (BALF) in Diagnosing Pneumonia of Children

Application of Metagenomic Next-Generation Sequencing (mNGS) Using Bronchoalveolar Lavage Fluid (BALF) in Diagnosing Pneumonia of Children

ABSTRACT Pneumonia is the leading cause of death in children; the pathogens are often difficult to diagnose. In this study, the performance of metagenomic next-generation sequencing (mNGS) using bronchoalveolar lavage fluid (BALF) samples from 112 children with confirmed pneumonia has been evaluated...

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Bibliographic Details
Main Authors: Aimei Yang, Chen Chen, Yan Hu, Guilang Zheng, Peiling Chen, Zhiwei Xie, Huifeng Fan, Yueyu Sun, Peiqiong Wu, Wenhui Jiang, Chun Wang, Jingwen Zhang, Dongwei Zhang, Jing Wang, Xiaoyin Hu, Han Xia, Genquan Yin, Yuxiong Guo
Format: Article
Language:English
Published: American Society for Microbiology 2022-10-01
Series:Microbiology Spectrum
Subjects:
metagenomic next-generation sequencing (mNGS)
bronchoalveolar lavage fluid (BALF)
pneumonia
children
culture
diagnosis
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01488-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.01488-22

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