Inhibition of type I interferon signaling abrogates early Mycobacterium bovis infection

Inhibition of type I interferon signaling abrogates early Mycobacterium bovis infection

Abstract Background Mycobacterium bovis (M. bovis) is the principal causative agent of bovine tuberculosis; however, it may also cause serious infection in human being. Type I IFN is a key factor in reducing viral multiplication and modulating host immune response against viral infection. However, t...

Full description

Bibliographic Details
Main Authors: Jie Wang, Tariq Hussain, Kai Zhang, Yi Liao, Jiao Yao, Yinjuan Song, Naveed Sabir, Guangyu Cheng, Haodi Dong, Miaoxuan Li, Jiamin Ni, Mazhar Hussain Mangi, Deming Zhao, Xiangmei Zhou
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Infectious Diseases
Subjects:
Immunity
Mycobacterium bovis
Type I interferon signaling
Inflammatory response
Macrophages polarization
Neutrophils
Online Access:https://doi.org/10.1186/s12879-019-4654-3

Internet

https://doi.org/10.1186/s12879-019-4654-3

Similar Items