Podophyllotoxin and its derivatives: Potential anticancer agents of natural origin in cancer chemotherapy

Podophyllotoxin and its derivatives: Potential anticancer agents of natural origin in cancer chemotherapy

The use of plant secondary metabolites has gained considerable attention among clinicians in the prevention and treatment of cancer. A secondary metabolite isolated mainly from the roots and rhizomes of Podophyllum species (Berberidaceae) is aryltetralin lignan - podophyllotoxin (PTOX). The purpose...

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Bibliographic Details
Main Authors: Sara Motyka, Karolina Jafernik, Halina Ekiert, Javad Sharifi-Rad, Daniela Calina, Basem Al-Omari, Agnieszka Szopa, William C. Cho
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Podophyllotoxin
Podophyllotoxin derivatives
Phytochemistry
Tumor cells
Pharmacology
Anticancer mechanisms
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222015347

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http://www.sciencedirect.com/science/article/pii/S0753332222015347

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