Activation of NRF2/HO-1 Pathway by aqueous methanolic leaf extract of Triclisia gilletii and selected identified compounds in Triclisia gilletii, modulates crystal binding genes (CD44/OPN) in Ethane-1,2-diol-induced nephrolithic rats

Background: Moonseed vine (Triclisia gilletii Staner) a member of the Menispermaceae family, has been previously investigated and reported in our laboratory to exhibit antilithiatic potentials against ethane-1,2-diol induced nephrolithiasis. However, the mechanism underlying its action is not clear....

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Bibliographic Details
Main Authors: Olanrewaju Sam Olayeriju, Olusola Olalekan Elekofehinti, Mary Tolulope Olaleye, Akintunde Afolabi Akindahunsi
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Phytomedicine Plus
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667031321000488