The Antiepileptic Drug and Toxic Teratogen Valproic Acid Alters Microglia in an Environmental Mouse Model of Autism

Autism spectrum disorder (ASD), a neurodevelopmental condition affecting approximately 1 in 44 children in North America, is thought to be a connectivity disorder. Valproic acid (VPA) is a multi-target drug widely used to treat epilepsy. It is also a toxic teratogen as well as a histone deacetylase...

Full description

Bibliographic Details
Main Authors: Korawin Triyasakorn, Ubah Dominic Babah Ubah, Brandon Roan, Minsyusheen Conlin, Ken Aho, Prabha S. Awale
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Toxics
Subjects:
Online Access:https://www.mdpi.com/2305-6304/10/7/379