High specificity of metagenomic next-generation sequencing using protected bronchial brushing sample in diagnosing pneumonia in children

BackgroundLower respiratory tract infections are the leading cause of morbidity and mortality in children worldwide. Timely and accurate pathogen detection is crucial for proper clinical diagnosis and therapeutic strategies. The low detection efficiency of conventional methods and low specificity us...

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Bibliographic Details
Main Authors: Chunyan Zhang, Zheng Li, Mengyuan Wang, Jiemin Zhou, Wenwen Yu, Huifang Liu, Bingxue Hu, Shifu Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1165432/full