Cholinergic Degeneration and Alterations in the TrkA and p75NTR Balance as a Result of Pro-NGF Injection into Aged Rats

Learning and memory impairments occurring with Alzheimer's disease (AD) are associated with degeneration of the basal forebrain cholinergic neurons (BFCNs). BFCNs extend their axons to the hippocampus where they bind nerve growth factor (NGF) which is retrogradely transported to the cell body....

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Bibliografiska uppgifter
Huvudupphovsmän: Ashley M. Fortress, Mona Buhusi, Kris L. Helke, Ann-Charlotte E. Granholm
Materialtyp: Artikel
Språk:English
Publicerad: Hindawi Limited 2011-01-01
Serie:Journal of Aging Research
Länkar:http://dx.doi.org/10.4061/2011/460543