Synthetic thiophenes induce chromosomal damage and trigger apoptosis in human cancer cell lines

Synthetic thiophenes induce chromosomal damage and trigger apoptosis in human cancer cell lines

Thiophenes are heterocyclic compounds containing a five-membered ring with sulphur as the heteroatom. This class of substances has been shown to have several biological activities, including specific anti-proliferative effects against some cancer cell lines. The aim of the present study was to evalu...

Full description

Bibliographic Details
Main Authors: Filipe N. Franco, Júlia T. Oliveira, Kimberly B. Tecchio, Flaviana A. Santos, Moacyr J.B.M. Rêgo, Francisco J.B. Mendonça-Júnior, Maira G.R. Pitta, Michelly C. Pereira, Rosy I.M.A. Ribeiro, Vanessa J.S.V. Santos, Fabio V. Santos
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:European Journal of Medicinal Chemistry Reports
Subjects:
Thiophene
Genotoxicity
Mutagenicity
In vitro
Anticancer candidate
Online Access:http://www.sciencedirect.com/science/article/pii/S277241742200005X

Internet

http://www.sciencedirect.com/science/article/pii/S277241742200005X

Similar Items