4-Hydroxyisoleucine relieves inflammation through iRhom2-dependent pathway in co-cultured macrophages and adipocytes with LPS stimulation

4-Hydroxyisoleucine relieves inflammation through iRhom2-dependent pathway in co-cultured macrophages and adipocytes with LPS stimulation

Abstract Background 4-Hydroxyisoleucine (4-HIL) is an active ingredient extracted from Trigonella foenum-graecum L., a Chinese traditional herbal medicine, which exerts the efficacy of anti-obesity and anti-diabetes. We previously reported that 4-HIL potentiates anti-inflammatory and anti-insulin re...

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Bibliographic Details
Main Authors: Cong Zhou, Rui Chen, Feng Gao, Jiaoyue Zhang, Furong Lu
Format: Article
Language:English
Published: BMC 2020-12-01
Series:BMC Complementary Medicine and Therapies
Subjects:
4-hydroxyisoleucine
Trigonella foenum-graecum L.
Obesity-induced inflammation
iRhom2
RAW264.7 macrophages
3 T3-L1 adipocytes
Online Access:https://doi.org/10.1186/s12906-020-03166-1

Internet

https://doi.org/10.1186/s12906-020-03166-1

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