αVβ3 Integrin Expression Is Essential for Replication of Mosquito and Tick-Borne Flaviviruses in Murine Fibroblast Cells

αVβ3 Integrin Expression Is Essential for Replication of Mosquito and Tick-Borne Flaviviruses in Murine Fibroblast Cells

The <i>Flavivirus</i> genus includes a number of important viruses that are pathogenic to humans and animals and are responsible for outbreaks across the globe. Integrins, a family of heterodimeric transmembrane molecules expressed in all nucleated cells mediate critical functions of cel...

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Bibliographic Details
Main Authors: Vinicius Pinho dos Reis, Markus Keller, Katja Schmidt, Rainer Günter Ulrich, Martin Hermann Groschup
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Viruses
Subjects:
integrins
flavivirus
host cell factors
virus binding
virus internalization
virus replication
Online Access:https://www.mdpi.com/1999-4915/14/1/18

Internet

https://www.mdpi.com/1999-4915/14/1/18

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