In-silico analyses provide strong statistical evidence for intra-species recombination events of the gyrA and CmeABC operon loci contributing to the continued emergence of resistance to fluoroquinolones in natural populations of Campylobacter jejuni

In-silico analyses provide strong statistical evidence for intra-species recombination events of the gyrA and CmeABC operon loci contributing to the continued emergence of resistance to fluoroquinolones in natural populations of Campylobacter jejuni

ABSTRACT: Objectives: The continued emergence of Campylobacter jejuni strains resistant to fluoroquinolones (FQs) has posed a significant threat to global public health, leading frequently to undesirable outcomes of human campylobacteriosis treatment. The molecular genetic mechanisms contributing t...

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Bibliographic Details
Main Authors: Rusudan Tsiklauri, Ekaterine Gabashvili, Saba Kobakhidze, Leila Tabatadze, Ekaterine Bobokhidze, Ketevan Dadiani, Stylianos Koulouris, Mamuka Kotetishvili
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Antimicrobial resistance
Genetic recombination
Campylobacter
Fluoroquinolone
Allelic exchange
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716522002016

Internet

http://www.sciencedirect.com/science/article/pii/S2213716522002016

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