HLA‐DR3介导的CD4 T细胞对1型糖尿病患者GAD65的应答
Abstract Aim We planned this study to identify diabetogenic glutamic acid decarboxylase (GAD65) peptides possibly responsible for human leucocyte antigen (HLA)‐DR3/DQ2‐mediated activation of GAD65‐specific CD4 T cells in type 1 diabetes (T1D). Methods Top 30 GAD65 peptides, found to strongly bind in...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2023-07-01
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Series: | Journal of Diabetes |
Subjects: | |
Online Access: | https://doi.org/10.1111/1753-0407.13406 |