HLA‐DR3介导的CD4 T细胞对1型糖尿病患者GAD65的应答

Abstract Aim We planned this study to identify diabetogenic glutamic acid decarboxylase (GAD65) peptides possibly responsible for human leucocyte antigen (HLA)‐DR3/DQ2‐mediated activation of GAD65‐specific CD4 T cells in type 1 diabetes (T1D). Methods Top 30 GAD65 peptides, found to strongly bind in...

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Bibliographic Details
Main Authors: Neihenuo Chuzho, Neetu Mishra, Nikhil Tandon, Uma Kanga, Gunja Mishra, Akanksha Sharma, Narinder K. Mehra, Neeraj Kumar
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:Journal of Diabetes
Subjects:
Online Access:https://doi.org/10.1111/1753-0407.13406