A Live-Attenuated Prime, Inactivated Boost Vaccination Strategy with Chimeric Hemagglutinin-Based Universal Influenza Virus Vaccines Provides Protection in Ferrets: A Confirmatory Study

Influenza viruses cause severe diseases and mortality in humans on an annual basis. The current influenza virus vaccines can confer protection when they are well-matched with the circulating strains. However, due to constant changes of the virus surface glycoproteins, the vaccine efficacy can drop s...

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Bibliographic Details
Main Authors: Raffael Nachbagauer, Florian Krammer, Randy A. Albrecht
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Vaccines
Subjects:
Online Access:http://www.mdpi.com/2076-393X/6/3/47