Properties of repression condensates in living Ciona embryos

While recent studies suggest that transcriptional activators form condensates at active loci, less is known about the distribution of repressor proteins. Here, the authors develop an expression assay in living Ciona embryos and visualize puncta of Hes repressors, with the Groucho/TLE corepressor, ob...

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Bibliographic Details
Main Authors: Nicholas Treen, Shunsuke F. Shimobayashi, Jorine Eeftens, Clifford P. Brangwynne, Michael Levine
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21606-5