Targeted in vitro gene silencing of E2 and nsP1 genes of chikungunya virus by biocompatible zeolitic imidazolate framework

Targeted in vitro gene silencing of E2 and nsP1 genes of chikungunya virus by biocompatible zeolitic imidazolate framework

Chikungunya fever caused by the mosquito-transmitted chikungunya virus (CHIKV) is a major public health concern in tropical, sub-tropical and temperate climatic regions. The lack of any licensed vaccine or antiviral agents against CHIKV warrants the development of effective antiviral therapies. Smal...

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Bibliographic Details
Main Authors: Rajarshee Tagore, Kalichamy Alagarasu, Poonam Patil, Suneela Pyreddy, Shakil Ahmed Polash, Mahadeo Kakade, Ravi Shukla, Deepti Parashar
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
chikungunya virus
gene silencing
metal-organic framework
zeolitic imidazolate frameworks
siRNA
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.1003448/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.1003448/full

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