FM1-43 is a permeant blocker of mechanosensitive ion channels in sensory neurons and inhibits behavioural responses to mechanical stimuli

<p>Abstract</p> <p>The molecular identity and pharmacological properties of mechanically gated ion channels in sensory neurons are poorly understood. We show that FM1-43, a styryl dye used to fluorescently label cell membranes, permeates mechanosensitive ion channels in cultured do...

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Bibliographic Details
Main Authors: Drew Liam J, Wood John N
Format: Article
Language:English
Published: SAGE Publishing 2007-01-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/3/1/1