Osteocyte Wnt/β-catenin pathway activation upon mechanical loading is altered in ovariectomized mice

Estrogen levels decline in both sexes with age, but more dramatically in females. Activation of the Wnt/β-catenin signaling pathway is central to the regulation of bone mass accrual and maintenance and in response to mechanical loading. Using the ovariectomized mouse model we examined the effect of...

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Bibliographic Details
Main Authors: Erica Jackson, Nuria Lara-Castillo, Mohammed P. Akhter, Mark Dallas, JoAnna M. Scott, Thiagarajan Ganesh, Mark L. Johnson
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Bone Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187221003867