Engineering a Pseudo-26-kDa <i>Schistosoma</i> Glutathione Transferase from <i>bovis</i>/<i>haematobium</i> for Structure, Kinetics, and Ligandin Studies

Engineering a Pseudo-26-kDa <i>Schistosoma</i> Glutathione Transferase from <i>bovis</i>/<i>haematobium</i> for Structure, Kinetics, and Ligandin Studies

Glutathione transferases (GSTs) are the main detoxification enzymes in schistosomes. These parasitic enzymes tend to be upregulated during drug treatment, with <i>Schistosoma haematobium</i> being one of the species that mainly affect humans. There is a lack of complete sequence informat...

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Bibliographic Details
Main Authors: Neo Padi, Blessing Oluebube Akumadu, Olga Faerch, Chinyere Aloke, Vanessa Meyer, Ikechukwu Achilonu
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biomolecules
Subjects:
<i>Schistosoma</i>
glutathione transferase
praziquantel
CDNB assay
kinetics
isothermal titration calorimetry
Online Access:https://www.mdpi.com/2218-273X/11/12/1844

Internet

https://www.mdpi.com/2218-273X/11/12/1844

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