Residual γH2AX foci as an indication of lethal DNA lesions

<p>Abstract</p> <p>Background</p> <p>Evidence suggests that tumor cells exposed to some DNA damaging agents are more likely to die if they retain microscopically visible γH2AX foci that are known to mark sites of double-strand breaks. This appears to be true even after...

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Bibliographic Details
Main Authors: Banuelos C Adriana, MacPhail Susan H, Klokov Dmitry, Banáth Judit P, Olive Peggy L
Format: Article
Language:English
Published: BMC 2010-01-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/4