Pseudomonas aeruginosa Lipoxygenase LoxA Contributes to Lung Infection by Altering the Host Immune Lipid Signaling

Pseudomonas aeruginosa Lipoxygenase LoxA Contributes to Lung Infection by Altering the Host Immune Lipid Signaling

Pseudomonas aeruginosa is an opportunistic bacteria and a major cause of nosocomial pneumonia. P. aeruginosa has many virulence factors contributing to its ability to colonize the host. LoxA is a lipoxygenase enzyme secreted by P. aeruginosa that oxidizes polyunsaturated fatty acids. Based on previo...

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Bibliographic Details
Main Authors: Eric Morello, Teresa Pérez-Berezo, Chloé Boisseau, Thomas Baranek, Antoine Guillon, Déborah Bréa, Philippe Lanotte, Xavier Carpena, Nicolas Pietrancosta, Virginie Hervé, Reuben Ramphal, Nicolas Cenac, Mustapha Si-Tahar
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Microbiology
Subjects:
Pseudomonas aeruginosa
lipoxygenase
lungs
infection
lipid mediators
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01826/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.01826/full

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