A Toll‐like receptor‐4/NLRP3 inflammasome pathway promotes inflammation in skeletal muscle of chronic kidney disease patients

A Toll‐like receptor‐4/NLRP3 inflammasome pathway promotes inflammation in skeletal muscle of chronic kidney disease patients

Abstract Background An emerging hypothesis is that the activation of innate immunity in the muscle of patients with chronic kidney disease (CKD) is implicated in the development and progression of wasting and cachexia. We previously observed that Toll‐like receptor‐4 (TLR4) and its downward NF‐κB‐de...

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Bibliographic Details
Main Authors: Daniela Verzola, Pasquale Esposito, Samantha Milanesi, Michela Saio, Daniela Picciotto, Marco Frascio, Alessandro Laudon, Giacomo Garibotto, Giuliano Brunori, Francesca Viazzi
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:JCSM Rapid Communications
Subjects:
Cachexia
CKD
Inflammasome
Oxidative stress
Online Access:https://doi.org/10.1002/rco2.75

Internet

https://doi.org/10.1002/rco2.75

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