FOXM1 is critical for the fitness recovery of chromosomally unstable cells
Abstract Tumor progression and evolution are frequently associated with chromosomal instability (CIN). Tumor cells often express high levels of the mitotic checkpoint protein MAD2, leading to mitotic arrest and cell death. However, some tumor cells are capable of exiting mitosis and consequently inc...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-07-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-023-05946-2 |