FOXM1 is critical for the fitness recovery of chromosomally unstable cells

Abstract Tumor progression and evolution are frequently associated with chromosomal instability (CIN). Tumor cells often express high levels of the mitotic checkpoint protein MAD2, leading to mitotic arrest and cell death. However, some tumor cells are capable of exiting mitosis and consequently inc...

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Bibliographic Details
Main Authors: Fan Pan, Sara Chocarro, Maria Ramos, Yuanyuan Chen, Alicia Alonso de la Vega, Kalman Somogyi, Rocio Sotillo
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05946-2