Shared genomic segments analysis identifies MHC class I and class III molecules as genetic risk factors for juvenile idiopathic arthritis

Summary: Juvenile idiopathic arthritis (JIA) is a complex rheumatic disease encompassing several clinically defined subtypes of varying severity. The etiology of JIA remains largely unknown, but genome-wide association studies (GWASs) have identified up to 22 genes associated with JIA susceptibility...

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Bibliographic Details
Main Authors: Cecile N. Avery, Nicole D. Russell, Cody J. Steely, Aimee O. Hersh, John F. Bohnsack, Sampath Prahalad, Lynn B. Jorde
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:HGG Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2666247724000162