Localized Interleukin-12 for Cancer Immunotherapy

Localized Interleukin-12 for Cancer Immunotherapy

Interleukin-12 (IL-12) is a potent, pro-inflammatory type 1 cytokine that has long been studied as a potential immunotherapy for cancer. Unfortunately, IL-12's remarkable antitumor efficacy in preclinical models has yet to be replicated in humans. Early clinical trials in the mid-1990's sh...

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Váldodahkkit: Khue G. Nguyen, Maura R. Vrabel, Siena M. Mantooth, Jared J. Hopkins, Ethan S. Wagner, Taylor A. Gabaldon, David A. Zaharoff
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Frontiers Media S.A. 2020-10-01
Ráidu:Frontiers in Immunology
Fáttát:
interleukin-12 (IL-12)
cancer immunotherapy
cancer vaccine
cytokine delivery system
localized delivery
intratumoral administration
Liŋkkat:https://www.frontiersin.org/article/10.3389/fimmu.2020.575597/full

Interneahtta

https://www.frontiersin.org/article/10.3389/fimmu.2020.575597/full

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