Unraveling the genetic diversity and phylogeny of Leishmania RNA virus 1 strains of infected Leishmania isolates circulating in French Guiana.

Leishmania RNA virus type 1 (LRV1) is an endosymbiont of some Leishmania (Vianna) species in South America. Presence of LRV1 in parasites exacerbates disease severity in animal models and humans, related to a disproportioned innate immune response, and is correlated with drug treatment failures in h...

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Main Authors: Sourakhata Tirera, Marine Ginouves, Damien Donato, Ignacio S Caballero, Christiane Bouchier, Anne Lavergne, Eliane Bourreau, Emilie Mosnier, Vincent Vantilcke, Pierre Couppié, Ghislaine Prevot, Vincent Lacoste
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5531682?pdf=render