Paris saponin VII enhanced the sensitivity of HepG2/ADR cells to ADR via modulation of PI3K/AKT/MAPK signaling pathway

Paris saponin VII enhanced the sensitivity of HepG2/ADR cells to ADR via modulation of PI3K/AKT/MAPK signaling pathway

Abstract To find the effect of Paris saponin VII (PS VII)‐mediated PI3K/AKT/MAPK signaling pathway on the sensitivity of ADR‐resistant HepG2 cell (HepG2/ADR) cells to ADR. The proliferation inhibitory rates were detected by using MTT assay. Flow cytometry was employed to examine the intracellular ac...

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Bibliographic Details
Main Authors: Gong‐En Tang, Yue‐Xiang Niu, Yun Li, Chao‐Yu Wu, Xiao‐Ying Wang, Jian Zhang
Format: Article
Language:English
Published: Wiley 2020-02-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
ADR
hepatocellular carcinoma
HepG2
Paris saponin VII
PI3K/AKT/MAPK
Online Access:https://doi.org/10.1002/kjm2.12145

Internet

https://doi.org/10.1002/kjm2.12145

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